Chemical Properties:
Package: Bottle, Aluminium foil bag, 25kg/Cardboard Drum, or according to customer's requirement. Storage Condition: Store in sealed containers at cool and dry (2~8℃) warehouse away from incompatible substances. Protect from light and moisture. Shipping: Deliver to worldwide by FedEx / DHL Express. Provide fast and reliable delivery. Shanghai Ruifu Chemical Co., Ltd. is the leading manufacturer of 1-Boc-Pyrrolidine-3-Carboxylic Acid (CAS: 59378-75-5) with high quality. Ruifu Chemical can provide worldwide delivery, competitive price, small and bulk quantities available. Purchase 1-Boc-Pyrrolidine-3-Carboxylic Acid, Please contact: alvin@ruifuchem.comDescription:
Package/Storage/Shipping:
| Chemical Name | 1-Boc-Pyrrolidine-3-Carboxylic Acid |
| Synonyms | N-Boc-Pyrrolidine-3-Carboxylic Acid; 1-Boc-3-Pyrrolidinecarboxylic Acid; 3-Carboxy-1-Boc-Pyrrolidine; 1-(tert-Butoxycarbonyl)-3-Pyrrolidinecarboxylic Acid; 1-(tert-Butoxycarbonyl)pyrrolidine-3-Carboxylic Acid; N-(tert-Butoxycarbonyl)pyrrolidine-3-carboxylic Acid; Pyrrolidine-1,3-Dicarboxylic Acid 1-tert-Butyl Ester; N-Boc-β-Proline; 1-N-Boc-beta-Proline |
| Stock Status | In Stock |
| CAS Number | 59378-75-5 |
| Molecular Formula | C10H17NO4 |
| Molecular Weight | 215.25 g/mol |
| Melting Point | 133.0 to 139.0℃ |
| Density | 1.20±0.06 g/cm3 |
| Sensitive | Heat Sensitive |
| Solubility | Soluble in Chloroform |
| Storage Temp. | Cool & Dry Place (2~8℃) |
| COA & MSDS | Available |
| Brand | Ruifu Chemical |
Advantages:
How to Purchase? Please contact Dr. Alvin Huang: sales@ruifuchem.com or alvin@ruifuchem.com 15 Years Experience? We have more than 15 years of experience in the manufacture and export of a wide range of high quality pharmaceutical intermediates or fine chemicals. Main Markets? Sell to domestic market, North America, Europe, India, Korea, Japanese, Australia, etc. Advantages? Superior quality, affordable price, professional services and technical support, fast delivery. Quality Assurance? Strict quality control system. Professional equipment for analysis include NMR, LC-MS, GC, HPLC, ICP-MS, UV, IR, OR, K.F, ROI, LOD, MP, Clarity, Solubility, Microbial limit test, etc. Samples? Most products provide free samples for quality evaluation, shipping cost should be paid by customers. Factory Audit? Factory audit welcome. Please make an appointment in advance. MOQ? No MOQ. Small order is acceptable. Delivery Time? If within stock, three days delivery guaranteed. Transportation? By Express (FedEx, DHL), by Air, by Sea. Documents? After sales service: COA, MOA, ROS, MSDS, etc. can be provided. Custom Synthesis? Can provide custom synthesis services to best fit your research needs. Payment Terms? Proforma invoice will be sent first after confirmation of order, enclosed our bank information. Payment by T/T (Telex Transfer), PayPal, Western Union, etc.FAQ:
Stable Supply: Maintain reasonable stock
Professional Service: One stop purchasing service
Technical Support: Technology solution available
Custom Synthesis Service: Ranged from grams to kilos
Fast Delivery: If within stock, three days delivery guaranteed
High Quality: Established a complete quality assurance system
Sufficient Capacity: Sufficient facilities and technicians
OEM Package: Custom package and label available
Specifications:
| Items | Inspection Standards | Results |
| Appearance | White or Light-Yellow Solid | White Solid |
| Melting Point | 133.0 to 139.0℃ | 137.0~138.0℃ |
| Water by Karl Fischer | <0.50% | 0.10% |
| Purity / Analysis Method | >98.0% (HPLC) | 98.1% |
| Infrared Spectrum | Conforms to Structure | Complies |
| 1H NMR Spectrum | Conforms to Structure | Complies |
| Conclusion | The product has been tested & complies with the given specifications | |
59378-75-5 - Risk and Safety:
Application:
Risk Codes R36/37/38 - Irritating to eyes, respiratory system and skin. R50/53 - Very toxic to aquatic organisms, may cause long-term adverse effects in the aquatic environment. R41 - Risk of serious damage to eyes Safety Description S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection. S61 - Avoid release to the environment. Refer to special instructions / safety data sheets. S60 - This material and its container must be disposed of as hazardous waste. S39 - Wear eye / face protection. UN IDs UN 3077 9/PG 3 WGK Germany 3 HS Code 2933990099 Hazard Class IRRITANT Packing Group Ⅲ 1-Boc-Pyrrolidine-3-Carboxylic Acid (CAS: 59378-75-5) is a pyrrole carboxylic acid compound, as an important intermediate of fine chemicals, it is widely used in the fields of medicine, food, pesticide, daily chemicals and so on. 1-Boc-Pyrrolidine-3-Carboxylic Acid is a reactant used in the synthesis of potent and highly selective ERK1,2 inhibitors.Synthesis Method:
With Pyrrolidine-3-Carboxylic Acid as raw material, the target compound, 1-Boc-Pyrrolidin-3-Carboxylic Acid, was prepared by reaction with di-tert-Butyl Dicarbonate under the condition of Et 3 N/MeOH for Boc protection. The reaction formula for preparation of 1-Boc-Pyrrolidin-3-Carboxylic Acid.